Overview

What is WISeR?

Importantly, WISeR does not change Medicare coverage or payment policy. It supports accurate, efficient compliance with existing National and Local Coverage Determinations.

The Wasteful and Inappropriate Service Reduction (WISeR) Model is a voluntary six-year CMS Innovation Center program designed to reduce unnecessary or inappropriate services in Original Medicare (Part A & B) for selected items and services. WISeR uses enhanced technologies—like AI and machine learning—combined with human clinical review to streamline decisions and protect beneficiaries and taxpayers.

WISeR launches January 1, 2026 and runs through December 31, 2031 in six pilot states: Arizona, New Jersey, Ohio, Oklahoma, Texas, and Washington. In New Jersey, WISeR prior authorization and pre-payment medical review activities are administered through Novitas (Jurisdiction H) with Genzeon providing the technology platform and operational support.

CMS WISeR Portal (NJ)

Register today to electronically submit prior authorization forms.

Program Process

How the WISeR Program Works

WISeR is built to make reviews more predictable and less burdensome, while aligning with existing Medicare rules.

WISeR Request Process:

  1. Provider submits a prior authorization (PA) request for a WISeR-included service rendered in New Jersey.
  2. Technology-enhanced review flags completeness.
  3. Review checks documentation against current Medicare coverage criteria.
  4. Human clinical validation occurs when needed to confirm medical necessity.
  5. Determination returned within CMS-defined timeframes.

If a claim is submitted without required PA, it may enter pre-payment medical review.

Services Requiring Prior Authorization

Nerve Stimulation

  • Electrical Nerve Stimulators
  • Sacral Nerve Stimulation for Urinary Incontinence
  • Phrenic Nerve Stimulator
  • Vagus Nerve Stimulation
  • Induced Lesions of Nerve Tracts
  • Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea

Pain and Spine*

  • Epidural Steroid Injections for Pain Management
  • Percutaneous Vertebral Augmentation (PVA) for Vertebral Compression Fracture (VCF)
  • Cervical Fusion

 

* REMOVED: Percutaneous Image-Guided Lumbar Decompression for Spinal Stenosis was removed from this list just before model initiation.

Skin and Tissue Substitutes

Only applicable to selected WISeR MAC jurisdictions and states with an active LCD in place during the WISeR PYs starting on January 1, 2026, as of November 21, 2025

  • Application of Bioengineered Skin Substitutes to Lower Extremity Chronic Non-Healing Wounds
  • Wound Application of Cellular and/or Tissue Based Products (CTPs), Lower Extremities

Other Services

  • Incontinence Control Devices
  • Diagnosis and Treatment of Impotence

References

Provider and Supplier Operational Guide

Wasteful and Inappropriate Service Reduction (WISeR) Model

Provider and Supplier Operational Guide, Version 2.0

Learn More

Model Details (CMS)

The Wasteful and Inappropriate Service Reduction (WISeR) Model will help protect American taxpayers by leveraging enhanced technologies, such as Artificial Intelligence (AI) and Machine Learning (ML), along with human clinical review, to ensure timely and appropriate Medicare payment for select items and services.

Read More

CMS WISeR Fact Sheet

Covers overview, goals, participation, coverage/payment policies, impact, and payment overview.

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WISeR Model Frequently Asked Questions

Common questions including those for coverage policies, protections of patients, and scope of services.

Learn More

Federal Register Notice

CMS-5056-N. Full document details as recorded in the Federal Register, as of July 1, 2025.

Read More
hip one

Genzeon User Guide for WISeR

How to use the Genzeon portal on HIP One to submit your electronic submissions under WISeR.

Download PDF

Frequently Asked Questions

No. WISeR uses existing Medicare coverage policies; it’s about how reviews happen, not what is covered.

If you need any assistance please email wiserhelpdesk@genzeon.com or visit our portal page at https://portal.hip.one/.

WISeR is a voluntary model for vendors/MAC operations, but prior authorization is required for included services furnished in pilot states.

Providers submit prior authorization requests to Genzeon or Novitas. The prior authorization request can be submitted via Genzeon’s portal, Novitasphere, by fax at (484) 200-2155, or by mail to Genzeon Corporation, 256 Eagleview Blvd, Suite 509, Exton, PA 19341. The coversheets can be accessed via Genzeon’s or Novitas’ websites.

When submitting prior authorization through the portals, the information will automatically transfer to the coversheet.

Prior authorization requests submitted directly to Genzeon are sent using Genzeon’s designated cover sheet and faxed to (484) 200-2155 or mailed to Genzeon Corporation, 256 Eagleview Blvd, Suite 509, Exton, PA 19341.

Prior authorization requests submitted to Novitas using the Novitas WISeR model coversheet, whether by fax, mail, or Novitasphere, will be forwarded to Genzeon.

A WISeR model prior authorization request requires specific elements to be present on the submission. To avoid potential dismissals due to an incomplete prior authorization request, submitters are highly encouraged to use the Genzeon or Novitas coversheet.

Providers can refer to the Wasteful and Inappropriate Service Reduction (WISeR) Model Provider and Supplier Operational Guide, Section 3.2: General Prior Authorization Request Documentation.

Yes, a third party can submit a prior authorization request on behalf of the provider or facility, provided the third party has access to the necessary information to submit a complete request.

CMS allows a physician or practitioner to submit a prior authorization request on behalf of a facility. Physicians and practitioners who submit the prior authorization request on behalf of a facility should include their contact information on the prior authorization request cover sheet, in addition to the facility’s contact information. If the physician or practitioner is not the requester and would like to obtain a copy of the decision notification, they should contact the facility.

All procedure codes within the same category that require prior authorization for the same beneficiary must be filed on a single claim and listed on the coversheet for review. The categories and codes are available in Appendix A of the Wasteful and Inappropriate Service Reduction (WISeR) Model Provider and Supplier Operational Guide.

Yes, the prior authorization request must list the number of units that are needed for the specific CPT code. Units are determined based on the HCPCS or CPT code descriptor for the service. Refer to Appendix A of the Wasteful and Inappropriate Service Reduction (WISeR) Model Provider and Supplier Operational Guide for specific code descriptors.

Once the procedure has started and needs to be changed to a different CPT code, you would verify that the new CPT code requires prior authorization, as outlined in Appendix A of the Wasteful and Inappropriate Service Reduction (WISeR) Model Provider and Supplier Operational Guide.

· Due to the timing of this discovery, prior authorization cannot be requested before the procedure. If the CPT code requires prior authorization, the claim will be filed with no UTN and will be stopped for prepayment review. An ADR letter will be sent requesting documentation for the service performed. When responding with documentation, please include the documentation sent for the original affirmed prior authorization request, the affirmed decision letter, and the documentation supporting the medically reasonable and necessary reason for switching the service CPT codes during the procedure.

· If the CPT code does not require prior authorization, the claim will be filed without the UTN and will process as usual.

A full list of FAQs can be found on the WISeR portal page, under Blogs: https://portal.hip.one/blog/faq-wiser-model.